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Promega fugene 6 transfection reagent kit
Fugene 6 Transfection Reagent Kit, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fugene+6+transfection+reagent/fugene+hd/pmc11406263__pnas__2408262121__sapp-23-5-10
Average 90 stars, based on 1 article reviews
fugene 6 transfection reagent kit - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Transfection:

Article Title: An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
Article Snippet: .. A549 and SK-MES-1 cells were transiently transfected with 2 μg of indicated sup-tRNA plasmid (or an empty vector) using FuGENE ® 6 Transfection Reagent (Promega), whereas C2BBe1 cells were transfected using PEI-MAX (Kyfora Bio) in DMEM. .. Forty-eight hours post-transfection, cells were washed twice with 2 ml of ice-cold PBS and then lysed in 150 μl RIPA Lysis and Extraction Buffer (Thermo Scientific), supplemented with PierceTM Protease Inhibitor Tablets (Thermo Scientific) for 30 min on ice.

Article Title: Large-scale experimental assessment of variant effects on the structure and function of the citrate transporter SLC13A5
Article Snippet: .. Briefly, HEK293T LLP-iCasp9-Blast cells were seeded in six-well plates at a density of 300,000 cells per well for 24 hours before co-transfection of pCAG-NLS-HA-Bxb1 and either the attB_Strp_HA_Ct-SLC13A5 single variant plasmid or the attB_Strp_HA_Ct_SLC13A5_Library_BC1_BC2 plasmid, with FuGENE 6 Transfection Reagent (Promega, E2691) according to the manufacturer’s protocol, for 72 hours. .. Following transfection, cells were treated with dox (2 μg/ml) for 24 hours before treatment with 10 nM AP1903 (MedChemExpress, 195514-63-7) for 24 to 48 hours (with fresh medium exchange every 24 hours).

Article Title: OICR-41103 as a chemical probe for the DCAF1 WD40 domain
Article Snippet: WD40 (1038-1400aa) DCAF1-smBiT and LgBiT-Vpr cDNA constructs were synthesized and cloned into pcDNA3.1 (+) plasmids by GeneArt Gene Synthesis (Invitrogen), while smBiT-MDM2 and LgBiT-p53 cDNA constructs (NanoBiTTM PPI Control Pair) were purchased from Promega (CS1603B09). .. HEK293EMT cells were transfected with the respective construct pairs in a 1:1 DNA ratio and 3:1 DNA to FuGENE® 6 Transfection Reagent (Promega; E2691). .. After 16–24 h of transfection, cells were seeded in 96-well white plates (PerkinElmer; 6005680).

Article Title: An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
Article Snippet: NCI-H1299 cells were seeded in a six-well plate at a density of 2.7 × 10 5 cells per well and cultured in RPMI media (Gibco) supplemented with 10% FBS (Gibco) and 1% penicillin–streptomycin (PS). .. Twenty-four hours after seeding, cells were transfected with 1 μg of the indicated tRNA plasmid using Fugene ® 6 Transfection Reagent (Promega). .. Cells were incubated at 37°C until RNA collection at 24, 48, or 72 h. Total RNA was extracted using the RNeasy Plus Mini Kit (Qiagen) following Appendix D: Purification of Total RNA Containing Small RNAs from Cells.

Article Title: An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
Article Snippet: NCI-H1299 cells were seeded in a 96-well plate at 9 × 10 3 cells per well and cultured in RPMI 1640 medium (ATCC) supplemented with 10% FBS (Gibco). .. The following day, cells were transfected with 100 ng of plasmid containing the indicated sup-tRNA gene under control of the 7SK promoter and wild-type SEAP under a CMV promoter, using FuGENE ® 6 Transfection Reagent (Promega). .. Cell viability and SEAP activity were measured 48 h post-transfection using WST-1 cell proliferation reagent (Sigma) and NovaBright Phopha-Light Assay Kit (Invitrogen), respectively, according to the manufacturers’ protocols.

Article Title: An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
Article Snippet: The following day, cells were transfected with 50 ng of the indicated sup-tRNA plasmid (or an empty vector), 50 ng of p53-dependent Fluc reporter plasmid PG13-luc (a gift from Bert Vogelstein; Addgene Plasmid # 16442; http://n2t.net/addgene:16442; RRID:ADDGENE_16442 ), and 15 ng of pLX313- Renilla . .. A549 and SK-MES-1 cells were transfected with FuGENE ® 6 Transfection Reagent (Promega), whereas C2BBe1 cells were transfected with PEI-MAX (Kyfora Bio). .. Firefly and Renilla luciferase activities were quantified 48 h post-transfection using the Dual-GloTM Luciferase Assay System (Promega) according to the manufacturer’s protocol.

Article Title: An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
Article Snippet: NCI-H1299 cells (2.5 × 10 5 ) were seeded in a T-25 flask and grown in RPMI 1640 medium (ATCC) supplemented with 10% FBS (Gibco). .. The following day, cells were transfected with 5 μg of GFP plasmid using FuGENE ® 6 Transfection Reagent (Promega). ..

Plasmid Preparation:

Article Title: An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
Article Snippet: .. A549 and SK-MES-1 cells were transiently transfected with 2 μg of indicated sup-tRNA plasmid (or an empty vector) using FuGENE ® 6 Transfection Reagent (Promega), whereas C2BBe1 cells were transfected using PEI-MAX (Kyfora Bio) in DMEM. .. Forty-eight hours post-transfection, cells were washed twice with 2 ml of ice-cold PBS and then lysed in 150 μl RIPA Lysis and Extraction Buffer (Thermo Scientific), supplemented with PierceTM Protease Inhibitor Tablets (Thermo Scientific) for 30 min on ice.

Article Title: Large-scale experimental assessment of variant effects on the structure and function of the citrate transporter SLC13A5
Article Snippet: .. Briefly, HEK293T LLP-iCasp9-Blast cells were seeded in six-well plates at a density of 300,000 cells per well for 24 hours before co-transfection of pCAG-NLS-HA-Bxb1 and either the attB_Strp_HA_Ct-SLC13A5 single variant plasmid or the attB_Strp_HA_Ct_SLC13A5_Library_BC1_BC2 plasmid, with FuGENE 6 Transfection Reagent (Promega, E2691) according to the manufacturer’s protocol, for 72 hours. .. Following transfection, cells were treated with dox (2 μg/ml) for 24 hours before treatment with 10 nM AP1903 (MedChemExpress, 195514-63-7) for 24 to 48 hours (with fresh medium exchange every 24 hours).

Article Title: An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
Article Snippet: NCI-H1299 cells were seeded in a six-well plate at a density of 2.7 × 10 5 cells per well and cultured in RPMI media (Gibco) supplemented with 10% FBS (Gibco) and 1% penicillin–streptomycin (PS). .. Twenty-four hours after seeding, cells were transfected with 1 μg of the indicated tRNA plasmid using Fugene ® 6 Transfection Reagent (Promega). .. Cells were incubated at 37°C until RNA collection at 24, 48, or 72 h. Total RNA was extracted using the RNeasy Plus Mini Kit (Qiagen) following Appendix D: Purification of Total RNA Containing Small RNAs from Cells.

Article Title: An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
Article Snippet: NCI-H1299 cells were seeded in a 96-well plate at 9 × 10 3 cells per well and cultured in RPMI 1640 medium (ATCC) supplemented with 10% FBS (Gibco). .. The following day, cells were transfected with 100 ng of plasmid containing the indicated sup-tRNA gene under control of the 7SK promoter and wild-type SEAP under a CMV promoter, using FuGENE ® 6 Transfection Reagent (Promega). .. Cell viability and SEAP activity were measured 48 h post-transfection using WST-1 cell proliferation reagent (Sigma) and NovaBright Phopha-Light Assay Kit (Invitrogen), respectively, according to the manufacturers’ protocols.

Article Title: An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
Article Snippet: NCI-H1299 cells (2.5 × 10 5 ) were seeded in a T-25 flask and grown in RPMI 1640 medium (ATCC) supplemented with 10% FBS (Gibco). .. The following day, cells were transfected with 5 μg of GFP plasmid using FuGENE ® 6 Transfection Reagent (Promega). ..

Variant Assay:

Article Title: Large-scale experimental assessment of variant effects on the structure and function of the citrate transporter SLC13A5
Article Snippet: .. Briefly, HEK293T LLP-iCasp9-Blast cells were seeded in six-well plates at a density of 300,000 cells per well for 24 hours before co-transfection of pCAG-NLS-HA-Bxb1 and either the attB_Strp_HA_Ct-SLC13A5 single variant plasmid or the attB_Strp_HA_Ct_SLC13A5_Library_BC1_BC2 plasmid, with FuGENE 6 Transfection Reagent (Promega, E2691) according to the manufacturer’s protocol, for 72 hours. .. Following transfection, cells were treated with dox (2 μg/ml) for 24 hours before treatment with 10 nM AP1903 (MedChemExpress, 195514-63-7) for 24 to 48 hours (with fresh medium exchange every 24 hours).

Construct:

Article Title: OICR-41103 as a chemical probe for the DCAF1 WD40 domain
Article Snippet: WD40 (1038-1400aa) DCAF1-smBiT and LgBiT-Vpr cDNA constructs were synthesized and cloned into pcDNA3.1 (+) plasmids by GeneArt Gene Synthesis (Invitrogen), while smBiT-MDM2 and LgBiT-p53 cDNA constructs (NanoBiTTM PPI Control Pair) were purchased from Promega (CS1603B09). .. HEK293EMT cells were transfected with the respective construct pairs in a 1:1 DNA ratio and 3:1 DNA to FuGENE® 6 Transfection Reagent (Promega; E2691). .. After 16–24 h of transfection, cells were seeded in 96-well white plates (PerkinElmer; 6005680).

other:

Article Title: CDK8 Inhibition Releases the Muscle Differentiation Block in Fusion-driven Alveolar Rhabdomyosarcoma
Article Snippet: For each replicate, approximately 7×10 cells were transfected using Fugene 6 (Promega) transfection reagent as according to manufacturer’s protocol and grown in DMEM.

Control:

Article Title: An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations
Article Snippet: NCI-H1299 cells were seeded in a 96-well plate at 9 × 10 3 cells per well and cultured in RPMI 1640 medium (ATCC) supplemented with 10% FBS (Gibco). .. The following day, cells were transfected with 100 ng of plasmid containing the indicated sup-tRNA gene under control of the 7SK promoter and wild-type SEAP under a CMV promoter, using FuGENE ® 6 Transfection Reagent (Promega). .. Cell viability and SEAP activity were measured 48 h post-transfection using WST-1 cell proliferation reagent (Sigma) and NovaBright Phopha-Light Assay Kit (Invitrogen), respectively, according to the manufacturers’ protocols.



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